Institute Director

M. Frederick Hawthorne was born in Fort Scott, Kansas and he received his elementary and secondary education in Kansas and Missouri. Prior to high school graduation, through examination he entered the Missouri School of Mines and Metallurgy, Rolla, Missouri as a chemical engineering student. He then transferred to Pomona College, Claremont, California and received a B.A. degree in chemistry. Hawthorne immediately commenced graduate work in organic chemistry at the University of California, Los Angeles, where he received his Ph.D. Iowa State University, Ames, Iowa then attracted Hawthorne as a postdoctoral associate (physical-organic chemistry) for a period of sixteen months. He joined the Rohm and Haas Company, Redstone Arsenal Research Division, Huntsville, Alabama as a Senior Research Chemist. Hawthorne launched his career in borane cluster chemistry by organizing and leading the Organometallic Chemistry Group at Rohm and Haas, Redstone. While on leave of absence from Rohm and Haas he served as a Visiting Lecturer in physical-organic chemistry at Harvard University, Cambridge, Massachusetts. Hawthorne served as a Laboratory Head at the Rohm and Haas Co., Philadelphia, Pennsylvania and in 1962, he became a full Professor at the University of California, Riverside. He transferred to the Los Angeles campus in 1969. In 1998 he was appointed University Professor of Chemistry, the most distinguished title bestowed upon faculty by the Regents of the University of California. Hawthorne joins twenty colleagues sharing this title University-wide.  In 2006 Hawthorne retired from UCLA and founded the International Institute of Nano and Molecular Medicine at the University of Missouri, where he is Institute Director and Curators’ Distinguished Professor of Chemistry and Radiology.

Hawthorne is the author or co-author of more than 560 research papers, 30 patents and 10 book chapters that reflect the joint efforts of approximately 200 Ph.D. students and postdoctoral associates and 11 Ph.D. coworkers at Rohm and Haas, Redstone. His students and postdoctoral associates represent 21 different countries and 35 of them now occupy academic positions. One of them was a space shuttle astronaut; Anna Lee Fisher (née Sims), M.S. (chemistry), M.D.

Fred Hawthorne Photo


M. Frederick Hawthorne

(573) 882-7016

Advisory Positions

National Research Council - U.S. National Academy of Sciences - Member of the Review Panel on U.S.-Soviet Scientific Exchange (National Academy of Sciences) and a co-author of the Kaysen Panel Report (Chemistry Section), 1975-76; Chemistry Member of the Board on International Scientific Exchange (National Academy of Sciences), 1975-78; National Academy of Sciences Board of Army Science and Technology and under these auspices chaired an oversight panel concerned with the conduct of Chemical Defense Research at the U. S. Army Chemical Research, Development and Engineering Center during 1985-89.

Department of Defense - U.S. Air Force Scientific Advisory Board, Office of the Secretary of the Air Force, 1980-86; Consultant to the Defense Science Board Task Force Study on the Detection and Neutralization of Illegal Drugs and Terrorist Devices, 1987-88; Member of the Board of Army Science and Technology for the U.S. National Academies of Science, 2005-10; Chemical Demilitarization Committee, 2009-2013.

Department of Energy - Director's External Advisory Board, The Los Alamos National Laboratory, 1991-92; Member of the Executive Committee of the International Society for Neutron Capture Therapy, 1992-98; President of International Society for Neutron Capture Therapy, 1996-98; Member of the Environmental and Energy Sciences Division Review Committee of the Idaho National Engineering and Environmental Laboratory, 2001.

Selected Professional Memberships

1973 U.S. National Academy of Sciences
1975 American Academy of Arts and Sciences
1976 Cosmos Club, Washington, D.C.
1980 American Association for the Advancement of Science
1995 Göttingen Academy of Sciences
2009 Fellow, American Chemical Society
2015 National Academy of Inventors


Inorganic Chemistry  - Associate Editor 1966-69; Editor-in-Chief 1969-2001
Bioconjugate Chemistry - Editorial Advisory Board


1963 Alfred P. Sloan Research Fellowship
1968 Chancellor's Award for Research at the University of California, Riverside.
1972 UCLA McCoy Award for Contributions to Chemistry
1973 The American Chemical Society Award in Inorganic Chemistry
1974 Honorary Sc.D. degree - Pomona College, California
1986 U. S. Air Force Meritorious Civilian Service Medal
1986 Richard C. Tolman Medal Award of the Southern California Section of the American Chemical Society
1986 Fellow of the Japan Society for the Promotion of Science
1988 First recipient of the Boron USA Award for Distinguished Achievements in Boron Chemistry
1988 American Chemical Society Award for Distinguished Service in the Advancement of Inorganic Chemistry.
1990 Alexander von Humboldt Foundation Award for Senior U.S. Scientists.
1990 Distinguished Visiting Professor - Ohio State University
1991Bailar Medal for Achievement in Inorganic Chemistry
1992 Ph.D., honoris causa, by Uppsala University, Uppsala, Sweden
1993 Polyhedron Medal and Prize for Creativity in Inorganic and Organometallic Chemistry.
1994 Chemical Pioneer Award of the American Institute of Chemists
1994 Recipient of the Willard Gibbs Medal presented by the Chicago Section of the American Chemical Society.
1996 Polyhedral Borane Chemistry Award - IMEBORON International Committee on Boron Chemistry
1997 U.S. National Academy of Sciences Award in Chemical Sciences
1997 Seaborg Medal - UCLA Association of Chemists and Biochemists
1998 Centenary Lectureship - The Royal Society of Chemistry
2001 Basolo Medal of the Chicago Section of the American Chemical Society
2003 Co-winner of the King Faisal International Prize for Science
2003 Monie A. Ferst Award - Georgia Institute of Technology Chapter of Sigma Xi Society
2009 Priestley Medal - The American Chemical Society
2009 Fellow of the American Chemical Society
2009 Honored with the Missouri State Senate’s Resolution of Appreciation for Scientific Achievements.
2010 Curators’ Distinguished Professor at the University of Missouri
2011 UCLA established the annual M. Frederick Hawthorne Lecture, with Hawthorne delivering the inaugural lecture.
2013 Recipient of the National Medal of Science, the highest honor bestowed by the country to scientists.


2016 568 Saurav J. Sarma, Aslam A. Khan, Lilit N. Goswami, Satish S. Jalisatgi, and M. Frederick Hawthorne. "A Trimodal Closomer Drug-Delivery System Tailored with Tracing and Targeting Capabilities." Chemistry, A European Journal. 2016. DOI: 10.1002/chem.2016022413.
  567 Alexander V. Safronov; Satish S. Jalisatgi; M. Frederick Hawthorne. "Synthesis of 10B-Enriched Sodium Borohydride." Inorganic Chemistry. 2016. DOI: 10.1021/acs.inorgchem.6b01002.
  566 Safronov, Alexander; Tran, Doanh; Sevryugina, Yulia; Jalisatgi, Satish S.; Hawthorne, M. Frederick. "Facile Synthesis of Mixed-Ligand Bis(dicarbollyl) Complexes of Nickel." Journal of Organometallic Chemistry, 2016, DOI: 10.1016/j.jorganchem.2016.01.002.
2015 565 Lalit N. Goswami, Lixin Ma, Quanyu Cai, Shatadru Chakravarty, Satish S. Jalisatgi and M. Frederick Hawthorne. “Synthesis, Relaxivity and In vivo Assessment of a Multimeric Gd-DTPA Conjugate of closo-Doedecaborate Dianion as Blood Pool MRI Contrast Agent.” Organic and Biomolecular Chemistry, 2015, 13, 8912-8918.
  564 Kabytaev, Kuanysh; Safronov, Alexander; Sevryugina, Yulia; Barnes, Charles; Jalisatgi, Satish; Hawthorne, M. Frederick. "Novel Synthetic Approach to Charge-Compensated Phosphonio-nido-Carboranes. Synthesis and Structural Characterization of Neutral Mono and Bis(Phosphonio) nido-ortho-Carboranes.", Inorganic Chemistry, 2015, 54 (8), pp4143-4150, DOI 10.1021/acs.inorgchem.5b00414.
  563 Elisa M. Heber, M. Frederick Hawthorne, Peter J. Kueffer, Marcella A Garabalino, Silvia I. Thorp, Emiliano C.C. Pozzi, Andrea Monti Hughes, Charles A. Maitz, Satish S. Jalisatgi, David W. Nigg, Paula Curotto, Veronica A. Trivillin, Amanda E. Schwint. “Therapeutic Efficacy of Boron Neutron Capture Therapy Mediated by Boron-rich Liposomes for Oral Cancer in the Hamster Cheek Pouch Model.” PNAS 2015,  54(1), 99-106.
  562 George R. Kracke, Yulia V. Sevryugina, Monika R. VanGordon, Peter J. Kueffer, Kuanysh Kabytaev, Satish S. Jalisatgi, M. Frederick Hawthorne. “Carborane Derived Local Anesthetics are Isomer Dependent.”  ChemMedChem2015, 10(1), 62-67. 
2014 561 Alexander Safronov, Natalia Shlyakhtina, Thomas Everett, Monika VanGordon, Yulia Sevryugina, Satish Jalisatgi, M. Frederick Hawthorne.  “Direct Observation of Bis(dicarbollyl)nickel Conformers in Solution by Fluorescence Spectroscopy: An Approach to Redox-Controlled Metallacarborane Molecular Motors.”  Inorganic Chemistry2014, 53, 10045-10053.
  560 Alexander V. Safronov, Kuanysh Z. Kabytaev, Satish S. Jalisatgi, M. Frederick Hawthorne.  “Novel Iodinated Carboranes: Synthesis of 8-Iodo-7,9-dicarba-nido-undecaborate Anion and 2-Iodo-1,7-dicarba-closo-dodecaborane.”  Dalton Trans., 2014,   DOI: 10.1039/C4DT00764F.
  559 Lalit N. Goswami, Aslam A. Khan, Satish S. Jalisatgi and M. Frederick Hawthorne.  “Synthesis and In Vitro Assessment of a Bifunctional Closomer Probe for Fluorine (19F) Magnetic Resonance and Optical Bimodal Cellular Imaging.”  Chem. Commun., 2014, 50 (43), 5793-5795.
  558 Kuanysh Z. Kabytaev, Alexander Valentinovich Safronov, Satish Jalisatgi, M. Frederick Hawthorne.  “Synthesis and Reactions of B-Vinylcarboranes.”  Journal of Organometallic Chemistry. 749 (2014) 106-108.
  557 Alexander Safronov, Yulia Sevryugina, Kothanda Pichaandi, Satish Jalisatgi, M. Frederick Hawthorne. “Synthesis of closo- and nido-Biscarboranes with Rigid Unsaturated Linkers as Precursors to Linear Metallacarborane-Based Molecular Rods.”  Dalton Transactions. 2014, 43 (13), 4969-4977.
2013 556 Oleg Bondarev, Aslam A. Khan, Xiaoyan Tu, Yulia V. Sevryugina, Satish S. Jalisatgi, M. Frederick Hawthorne.  “The Synthesis of [closo-B12(OH)11NH3]- : A New Heterobifunctional Dodecaborane Scaffold for Drug Delivery Applications.  J. Am. Chem. Society, 2013, 135(35), 13204-13211.
  555 Lalit N. Goswami, Lixin Ma, Peter J. Kueffer, Satish S. Jalisatgi and M. Frederick Hawthorne.  “Synthesis and Relaxivity Studies of a DOTA-based Nanomolecular Chelator Assembly Supported by an Icosahedral Closo-B122- -Core for MRI: A Click Chemistry Approach.”  Molecules 2013, 18(8), 9034-9048.
  554 M. Frederick Hawthorne.  “Interview with M. Frederick Hawthorne.”  Future Medicinal Chemistry. 2013, vol. 5, no. 6, 627-632.
  553 Alexei Pushechnikov, Satish S. Jalisatgi, M. Frederick Hawthorne.  “Dendritic closomers: novel spherical hybrid dendrimers.”  Chem. Commun2013, 49, 3579-3581.
  552 Peter J. Kueffer, Charles A. Maitz, Aslam A. Khan, Seth A. Schuster, Natalia I. Shlyakhtina, Satish S. Jalisatgi, John D. Brockman, David W. Nigg, M. Frederick Hawthorne. “Boron neutron capture therapy demonstrated in mice bearing EMT6 tumors following selective delivery of boron by rationally designed liposomes.”  PNAS  vol. 110,
no. 16, 6512-6517 (2013).
  551 Kuanysh Kabytaev, Alexander V. Safronov, Thomas A. Everett, Satish S. Jalisatgi, M. Frederick Hawthorne. “B-Mercaptocarboranes: A New Synthetic Route.”  European Journal of Inorganic Chemistry, 2013, 14, 2488-2491.
  550 Lalit Goswami, Lixin Ma, Shatadru Chakravarty, Quanyu Cai, Satish Jalisatgi, M. Frederick Hawthorne.  “Discrete Nanomolecular Polyhedral Borane Scaffold Supporting Multiple Gadolinium(III) Complexes as a High Performance MRI Contrast Agent.”  Inorg. Chem.  2013, 52 (4), 1694-1700.
  549 Lalit Goswami, Lixin Ma, Quanyu Cai, Saurav Sarma, Satish Jalisatgi, M. Frederick Hawthorne.  “cRGD Peptide-Conjugated Icosahedral closo-B122- Core Carrying Multiple Gd3+ -DOTA Chelates for ανβ3 Integrin-Targeted Tumor Imaging (MRI).”  Inorg. Chem. 2013, 52, 1701-1709.
2012 548 Lalit Goswami, Zachary Houston, Saurav Sarma, Hairong Li, Satish Jalisatgi, M. Frederick Hawthorne.  “Synthesis of Vertex-Differentiated Icosahedral closo-Boranes: Polyfunctional Scaffolds for Targeted Drug Delivery.”  Journal of Organic Chemistry.  2012, 77 (24), 11333-11338.
  547 J. Romanos, M. Beckner, D. Stalla, A. Tekeei, G. Suppes, S. Jalisatgi, M. Lee, F. Hawthorne, J.D. Robertson, L. Firlej, B. Kuchta, C. Wexler, P. Yu, P. Pfeifer.  “Infrared study of boron-carbon chemical bonds in boron-doped activated carbon.”  Carbon2012, 54, 208-214.
  546 Lalit Goswami, Zachary Houston, Satish S. Jalisatgi, M. Frederick Hawthorne.  “Efficient synthesis of diverse heterobifunctionalized clickable oligo (ethylene glycol) linkers for bioconjugation and drug delivery applications.”  Organic and Biomolecular Chemistry, 2012, 11, 1116-1126.
  545 M. F. Hawthorne, A. Pushechnikov. “IMEBORON-XIV: Polyhedral borane derivatives: Unique and versatile structural motifs.” Pure and Applied Chemistry.  Vol. 84, No. 11, 2279-2288 (2012).
  544 Oleg Bondarev, Yulia V. Sevryugina, Satish S. Jalisatgi, M. Frederick Hawthorne. “Acid-Induced Opening of [closo-B10H10]2- as a New Route to 6-Substituted nido-B10H13 Decaboranes and Related Carboranes.”  Inorg. Chem. 2012, 51, 9935-9942.
  543 Alexander V. Safronov, Yulia V. Sevryugina, Satish S. Jalisatgi, Robert D. Kennedy, Charles L. Barnesand M. Frederick Hawthorne “An Unfairly Forgotten Member of the Iodocarborane Family: Synthesis and Structural Characterization of 8-Iodo-1,2-dicarba-closo-dodecaborane, Its Precursors and Derivatives.”  Inorg. Chem. 2012, 51, 2629-2637.
  542 Elisa M. Heber, Peter J. Kueffer, Mark W. Lee Jr., M. Frederick Hawthorne, Marcela A. Garabalino, Ana J. Molinari, David W. Nigg, William Bauer, Andrea Monti Hughes, Emiliano C.C. Pozzi, Veronica A. Trivillin, Amanda E. Schwint “Boron delivery with liposomes for Boron Neutron Capture Therapy (BNCT):” Biodistribution studies in an experimental model of oral cancer demonstrating therapeutic potential.”  Radiation and Environmental Biophysics. 2012 51:195-204.
  541 Alexander V. Safronov, Natalia Shlyakhtina, M. Frederick Hawthorne “A New Approach to the Synthesis of 3-Alkyl-1,2-dicarba-closo-dodecaboranes: Reaction of Alkyldichloroboranes with Thallium Dicarbollide.” Organometallics, 31, 2764-2769 (2012).
2011 540 Satish S. Jalisatgi, Vikas S.Kulkarni, Betty Tang, Zachary H. Houston, Mark W. Lee, Jr. and M. Frederick Hawthorne “A Convenient Route to Diversely Substituted Icosahedral Closomer Nanoscaffolds.” Journal of the American Chemical Society, 133, 12382-12385 (2011).
  539 Oleg Bondarev and M. Frederick Hawthorne “Catalytic Hydroxylation of [Closo-B(12)H(12)](2-)-Adaptation of the Periana Reaction to a Polyhedral Borane.” Chemical Communications, 47, 6978 – 6980 (2011).
  538 Lalit N. Goswami, Shatadru Chakravarty, Mark W. Lee, Jr., Satish S. Jalisatgi and M. Frederick Hawthorne “Extensions of the Icosahedral Closomer Structure by Using Azide-Alkyne Click Reactions.” Angewandte Chemie International Edition in English, 50, 4689-4691 (2011).
  537 Alexander V. Safronov, Satish S. Jalisatgi, Han Baek Lee, and M. Frederick Hawthorne.  “Chemical Hydrogen Storage Using Polynuclear Borane Anion Salts”, Int. J. Hydrogen Energ., 36, 234-239 (2011).
  536 A. V. Safronov, M. F. Hawthorne. “Novel Synthesis of 3-iodo-ortho-carborane”, Inorg. Chim. Acta (2011), doi:10.1016/j.ica.2011.05.002.
2010 535 M. Frederick Hawthorne. “Advances at the Interface of Polyhedral Borane Chemistry and Medicine”, Comments on Inorganic Chemistry, 31: 3, 153 – 163 (2010).
  534 Yulia Sevryugina, Richard L. Julius, and M. Frederick Hawthorne, “Novel Approach to Aminocarboranes by Mild Amidation of Selected Iodo-carboranes”, Inorg. Chem., 49, 10627-10634 (2010).
  533 Steven D. Karlen, Horacio Reyes, R.E. Taylor, Saeed I. Khan, M. Frederick Hawthorne, and Miguel A. Garcia-Garibay.  “Symmetry and Dynamics of Molecular Rotors in Amphidynamic Molecular Crystals”, Proc. Natl. Acad. Sci. USA, 107, 14973 (2010).
2009 532 John D. Brockman, David .W. Nigg, M. Frederick Hawthorne, Mark W. Lee and Charles McKibben.  "Characterization of a boron neutron capture therapy beam line at the University of Missouri Research Reactor", J. Radioanal. Nucl. Chem., 282, 157-160 (2009).
  531 M. Frederick Hawthorne. “Boron, My Favorite Element”, J. Chem. Educ., 86(10), 1131 (2009).
  530 Robert D. Kennedy, Carolyn B. Knobler, and M. Frederick Hawthorne.  “Towards Unidirectional Rotary Motion in Nickelacarboranes: Characterization of Diastereomeric Nickel Bis(Dicarbollide) Complexes Derived from the [Nido-7-CH3-7,8-C2B9H11]– Anion”, Inorganic Chemistry, 48, 9377-9384 (2009).
  529 John D. Brockman, David .W. Nigg, M. Frederick Hawthorne, and Charles McKibben.  “Spectral performance of a composite single-crystal filtered thermal neutron beam for BNCT research at the University of Missouri”, Appl. Radiat. Isot., 67, 222-225 (2009).
2008 528 John D. Brockman, David. W. Nigg, M. Frederick Hawthorne, and Charles. McKibben.  “A new single-crystal filtered thermal neutron beam for BNCT research at the University of Missouri”, Proceedings from the International Conference on Reactor Physics, Nuclear Power: A Sustainable Resource, Casino-Kursaal Conference Center, Interlaken, Switzerland, (2008).
  527 R. L. Julius, & M. F. Hawthorne. “Amyloid Disease Prevention by Transthyretin Native State Complexation with Caroborane Derivatives Lacking Cyclooxygenase Inhibition”, Drug News and Perspectives, 21, 258 (2008).
  526 Michael F. Z. Page, Satish S. Jalisatgi, Andreas Maderna and M. Frederick Hawthorne, “Design and Synthesis of a Candidate α-Human Thrombin Irreversible Inhibitor Containing a Hydrophobic Carborane Pharmacophore”, Synthesis, No. 4, 555-563 (2008).
2007 525 D. Scott Wilbur, Ming-Kuan Chyan, Donald K. Hamlin, Robert L. Vesslla, Timothy J. Wedge, and M. Frederick Hawthorne. “Reagents for Astatination of Biomolecules. 2. Conjunction of Anionic Boron Cage Pendant Groups to a Protein Provides a Method for Direct Labeling that is Stable to in Vivo Deastatination”, Bioconjugate Chem., 18, 1126-1240 (2007).
  524 Omar K. Farha, Alexander M. Spokoyny, M. Frederick Hawthorne, Karen L. Mulfort, Chad A. Mirkin and Joseph T. Hupp, “Synthesis and Hydrogen Sorption of Carborane-based Met-organic Framework Materials”, J. Am. Chem. Soc., 129(42), 12680-12681 (2007).
  523 Zhu Yinghuai, Effendi Widaja, Shirley Lo Pei Sia, Wang Zhan, Keith Carpenter, John A. Maguire, Narayan S. Hosmane, and M. Frederick Hawthorne, “Ruthenium(0) Nanoparticle-Catalyzed Isotope Exchange between 10B and 11B Nuclei in Decaborane(14)”, J. Am. Chem. Soc. 129, 6507 (2007).
  522 Bradley W. Schuller, Arlin B. Rogers, Kathleen S. Cormier, Kent J. Riley, Peter J. Beinns,Richard Julius, M. Frederick Hawthorne, and Jeffrey A. Coderre, “No Significant Endothelial Apoptosis in the Radiation-Induced Gastrointestinal Syndrome”, Int. J. Radiation Oncology Biol. Phys., 68, 205 (2007).
  521 Richard L. Julius, Omar K. Farha, Janet Chiang, L. Jeanne Perry, and M. Frederick Hawthorne,“Synthesis and Evaluation of Transthyretin Amyloidosis Inhibitors Containing Carborane Pharmacophores”, Proc. Natl. Acad. Sci. USA, 104, 4808 (2007).
  520 Mark W. Lee, Omar K. Farha, M. Frederick Hawthorne, and Corwin H. Hansch, “Alkoxy Derivatives of Dodecaborate: Discrete Nanomolecular Ions with Tunable Pseudometallic Properties”, Angew. Chem. Int. Ed., 46, 3018 (2007).
2006 519 M. Frederick Hawthorne, Bhaskar M. Ramachandran, Robert D. Kennedy, Carolyn B. Knobler, “Approaches to Rotary Molecular Motors”, Proceedings of the Twelfth International Meeting on Boron Chemistry (IMEBORON XII), Pure Appl. Chem., 78, 1299-1304 (2006).
2005 518 Bradley W. Schuller. Peter J. Binns. Kent J. Riley, Ling Ma, Frederick Hawthorne, and Jeffrey A. Coderre, “ Selective Irradiation of the Vascular Endothelium Has No Effect on the Survival of Murine Intestinal Crypt Stem Cells”, Proc. Nat. Acad. Sci. 103 (10), 3787-3792 (2005).
  517 Omar K. Farha, Richard L. Julius, M. Frederick Hawthorne, “Synthesis of a Homotrifunctional Conjugation Reagent Based on Maleimide Chemistry”, Tetrahedron Letters, 47, 2619-2622 (2005).
  516 Tiejun Li, Julie Hamdi, and M. Frederick Hawthorne, “Unilamellar Liposomes with Enhanced Boron Content”, Bioconj. Chem., 17, 15-20 (2005).
515 Bhaskar M. Ramachandran and M. Frederick Hawthorne, "Synthesis and Structural Characterization of Symmetrical Closo-4,7-I 2-1,2-C2B10H10 and [(CH3)3NH][nido-2,4-I 2-7,8-C2B9H10]", Inorg. Chem., 45, 336-340 (2005).
  514 Tiejun Li, Satish S. Jalisatgi, Michael J. Bayer, Andreas Maderna, Saeed I. Khan, and M. Frederick Hawthorne, “Organic Syntheses on an Icosahedral Borane Surface: Closomer Structures with Twelvefold Functionality”, J. Am. Chem. Soc., 127, 17832-17841 (2005).
  513 Ling Ma, Julie Hamdi, Frances Wong, and M. Frederick Hawthorne, “Closomers of High Boron Content: Synthesis, Characterization, and Potential Application as Unimolecular Nanoparticle Delivery Vehicles for BNCT”, Inorg. Chem.,45, 278-285 (2005).
  512 Omar K. Farha, Richard L. Julius, Mark W. Lee, Ramon E. Huertas, Carolyn B. Knobler, and M. Frederick Hawthorne, “Synthesis of Stable Dodeca-(alkoxy) Derivatives of Hypercloso-B12H12”, J. Am. Chem. Soc., 127(51), 18243-18251 (2005).
  511 Bhaskar M. Ramachandran, Carolyn B. Knobler, and M. Frederick Hawthorne, “Example of an Intramolecular, Non-classical C-H--pHydrogen Bonding Interaction in an Arylcarborane Derivative”, J. Mol. Struct. (2005).
  510 Ling Ma, Julie Hamdi, Jiaxing Huang, and M. Frederick Hawthorne, “Camouflaged Carborane Amphiphiles: Synthesis and Self-assembly”, Inorg. Chem., 44, 7249-7258 (2005).
  509 Hershel Jude, Hendrik Disteldorf, Sonja Fischer, Timothy J. Wedge, Adam M. Hawkridge, Atta M. Arif, M. Frederick Hawthorne, David C. Muddiman, and Peter J. Stang, “Coordination Driven Self-assemblies with a Carborane Backbone”, J. Am. Chem. Soc., 127, 12131-12139 (2005).
508 Axel Herzog, Satish S. Jalisatgi, Carolyn B. Knobler, Timothy J. Wedge, and M. Frederick Hawthorne, “Camouflaged Carborarods Derived from B-permethyl-1,12-diethynyl-para-and B-octamethyl-1,7-diethynyl-meta-carborane Modules”, Chem. Eur. J11, 7155-7174 (2005).
2004 507 Michael J. Bayer, Satish S. Jalisatgi, Brian Smart, Axel Herzog, Carolyn B. Knobler, and M. Frederick Hawthorne, “B-Octamethyl-[12]Mercuracarborand–4 as Host for “Naked” Fluoride Ions”, Angew. Chem. Int. Ed.116, 1890-1893 (2004)
506 D. Scott Wilbur, Ming-Kuan Chyan, Donald K. Hamlin, Brian B. Kegley, Ruedi Risler, Pradip M. Pathare, Janna Quinn, Robert L. Vessella, Catherine Foulon, Michael Zalutsky, Timothy J. Wedge, and M. Frederick Hawthorne, “Reagents for Astatination of Biomolecules. Comparison of the In Vivo Distribution and Stability of Some Radioiodinated and Astatinated Benzamidyl- and nido-Carboranyl Compounds”, Bioconj. Chem., 15, 203-223 (2004).

505 M. Frederick Hawthorne, Jeffrey I. Zink, Johnny M. Skelton, Michael J. Bayer, Chris Liu, Ester Livshits, Roi Baer, and Daniel Neuhauser, “Electrical or Photocontrol of the Rotary Motion of a Metallacarborane”, Science303, 1849-1851 (2004). 


504 Timothy J. Wedge, Axel Herzog, Ramón Huertas, Mark W. Lee, Carolyn B. Knobler and M. Frederick Hawthorne, “Metal-Metal Communication Through Carborane Cages Supporting Electroactive [h5-CpFe(CO)2] Substituents”, Organometallics, 23, 482 (2004).


503 Michael J. Bayer and M. Frederick Hawthorne, “An Improved Method for the Synthesis of [Closo-B12(OH)12]2-,” Inorg. Chem., 43, 2018-2020 (2004).
 2003 502 Tiejun Li, Jason Thomas, and M. Frederick Hawthorne, “Liposomes from Novel Carborane-containing Lipids for Boron Neutron Capture Therapy”, Abstract of papers, 225 th Annual ACS meeting, March 25, 2003. (2003).


501 Sean L. Johnston, Mark W. Lee, and M. Frederick Hawthorne, “Development of Cell-surface Protein Targeted CT and MR Contrast Agents”, Applied Radiology (Supplement), 70-77 (2003).

500 M. Frederick Hawthorne, “New Discoveries at the Interface of Boron and Carbon Chemistries,” Pure Appl. Chem.75, 1157 (2003).[pdf]


499 M. Frederick Hawthorne, “Some Biomedical Applications of Aromatic Polyhedral Boranes and Their Progeny,” Special Publication of the King Faisal Foundation Honoring the King Faisal International Prize in Science 2003 (2003).


498 M. F Frederick Hawthorne, Satish Jalisatgi, Cynthia L. Beno, David E. Harwell and Carolyn B. Knobler, “Intra and Intermolecular Hydrogen Bonding in Some Cobaltacarboranes”, J. Mol. Struct., 656, 239-247 (2003).


497 M. Frederick Hawthorne and Mark W. Lee, “A Critical Assessment of Boron Target Compounds for Boron Neutron Capture Therapy”, J. Neuro-Oncol., 62, 33-45 (2003).


496 Yinghuai Zhu, Keith Carpenter, Ching Chi Bun, Stefan Bahnmueller, Chan Pek Ke, Venugopal    Shanmugham Srid, Leong Weng Kee, and M. Frederick Hawthorne, “(R)–Binap-Mediated Asymmetric Hydrogenation Using a Rhodacarborane Catalyst in Ionic Liquid Media,” Angew. Chem. Int. Ed. , 42, 3792 (2003).


495 Michael J. Bayer, Axel Herzog, Martin Diaz, George A. Harakas, Hans Lee, Carolyn B. Knobler, and M. Frederick Hawthorne, “The Synthesis of Carboracycles Derived from B,B`-Bis(aryl) Derivatives of Icosahedral ortho-Carborane,” Chem. Eur. J., 9, 2732 (2003). [pdf]
  494 Timothy J. Wedge and M. Frederick Hawthorne, “Multidentate Carborane-Containing Lewis Acids and Their Chemistry:Mercuracarborands,” Coord. Chem. Rev.  240, 111 (2003). [pdf]
2002 493 M. Frederick Hawthorne, “Further Advances at the Interface of Boron and Carbon Chemistries,” Proceedings of the Eleventh International Conference on Boron Chemistry, Published by the A. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Y. N. Bubanov, Editor., Moscow, Russia (2002).


492 Andreas Maderna Ramon Huertas, M. Frederick Hawthorne, Raymond Luguya, and M. Graca H. Vicente, “Synthesis of a Porphyrin-labeled Carboranyl Phosphate Diester: A Potential New Drug for Boron Neutron Capture Therapy,” Chem. Comm. 16, 1784(2002).


491 M. Frederick Hawthorne, Kenneth Shelly, and Fangbiao Li, “Versatile Chemistry of the [B20H18]2- Ions: Novel Reactions and Structural Motifs,” Chem. Comm., 547(2002).
2001 490 Mark B. Smuckler, Satish S. Jalisatgi, Lufeng Guan, Akira Nakanishi, Harumi Kasamatsu, and M. Frederick Hawthorne, “Boron-RichOligomeric Phosphate Diesters that Target the Cell Nucleus In Vitro,” Frontiers in Neutron Capture Therapy, Vol.2, M. Frederick Hawthorne, Kenneth Shelly and Richard J. Wiersema, Editors.  Kluwer Academic/Plenum Publishers: New York,  New York, 1103(2001).


489 Fangbiao Li, Kenneth Shelly, Carolyn B. Knobler and M. Frederick Hawthorne, “Benzoquinone Oxidation of the [ae-B20H17NH3]3- and [ae-B20H17OH]4- Ions,” Frontiers in Neutron Capture Therapy, Vol.2, M. Frederick Hawthorne, Kenneth Shelly, and Richard J.Wiersema, Editors.  Kluwer Academic/Plenum Publishers: New York,  New York, 807 (2001).


488 Toralf Peymann, Kenneth Shelly and M. Frederick Hawthorne, “Recent Developments in the Chemistry of [B12H12]2-,” Frontiers in Neutron Capture Therapy, Vol.2, M. Frederick Hawthorne, Kenneth Shelly and Richard J. Wiersema, Editors.  KluwerAcademic/Plenum Publishers: New York, New York, 775 (2001).
  487 Toralf Peymann, Carolyn B. Knobler, Saeed I. Khan and M. Frederick Hawthorne, “Dodecahydroxy-closo-dodecaborate (2-),” J. Am. Chem. Soc. 123, 2182 (2001).


486 K.J. Stelzer, P. R. Gavin, R. Risler, H. Kippenes, M. F. Hawthorne, D.W. Nigg and G. E. Laramore, “Boron Neutron Capture-Enhanced Fast Neutron Therapy (BNC/FNT) for Non-Small Cell Lung Cancer in Canine Patients,” Frontiers in Neutron Capture Therapy, Vol.1, M. Frederick Hawthorne, Kenneth Shelly and Richard J. Wiersema, Editors.  Kluwer Academic/Plenum Publishers: New York, New York, 735 (2001).


485 Axel Herzog, Carolyn B. Knobler and M. Frederick Hawthorne,  “Synthesis, Structure and Reactivity of closo-2,3,4,5,6,7,8,9,10,11-decahydroxy-1,12-bis-(sulfonicacid)-1,12-dicarbadodecaborane (12),” J. Am. Chem. Soc. 123, 12791 (2001).


484 Andreas Maderna, Axel Herzog Carolyn B. Knobler and M. Frederick Hawthorne, “The Syntheses of Amphiphilic CamouflagedCarboranes as Modules for Supramolecular Construction,” J. Am. Chem. Soc123, 10423 (2001).


483 M. Frederick Hawthorne, “Obituary:  Donald J. Cram (1919-2001),” Nature 412, 696 (2001).


482 George E. Laramore, K.J. Stelzer, R. Risler, J.L. Schwartz, J.J. Douglas, J.P. Einck, D.W. Nigg, C.A. Wemple, J.K. Hartwell, Y.D.Harker, Patrick R. Gavin and M. Frederick Hawthorne,  “Neutron Capture Therapy (NCT) Enhancement of Fast Neutron Radiotherapy:  Application to Non-Small Cell Lung Cancer,” Proceedings of the Sixteenth International Conference on Application of Accelerators in Research and Industry, J.L. Duggan and I.L. Morgan, Editors. American Institute of Physics (2001).


481 Jason Thomas and M. Frederick Hawthorne, “Dodeca(carboranyl)-substituted Closomers: Toward Unimolecular Nanoparticles as Delivery Vehicles for BNCT,” Chem. Comm.1884 (2001).


480 Theodore W. Bitner, Timothy J. Wedge, M. Frederick Hawthorne and Jeffrey I. Zink, “Synthesis and Luminescence Spetroscopy of a Series of [h5-CpFe(CO)2] Complexes Containing 1,12-Dicarba-closo-dodecaboranyl  and -ylene Ligands,” Inorg. Chem. 40, 5428 (2001).


479 Hans Lee, Carolyn B. Knobler and M. Frederick Hawthorne, “A Hydrogen Bonded [(Mercuracarborand-Water)2-Benzene] p-Sandwich Complex,” Angew. Chem. Int. Ed. 40, 3058 (2001).


478 Hans Lee, Carolyn B. Knobler and M. Frederick Hawthorne, “Octahedral Coordination of Halide Ions (I-, Br-, Cl-) Sandwich Bonded with Tridentate Mercuracarborand-3 Receptors,” J. Am. Chem. Soc. 123, 8543 (2001).


477 Hans Lee, Carolyn B. Knobler and M. Frederick Hawthorne, “Modular Self-Assembly of A Microporous Solid Based upon Mercuracarborand-4 and A New Bonding Motif,” Angew. Chem. Int. Ed. 40, 2124 (2001).


476 Axel Herzog, Ryan P. Callahan, Charles L.B. Macdonald, Vincent M. Lynch, M. Frederick Hawthorne and Richard J. Lagow, “APerfluorinated Nanosphere: Synthesis and Structure of Perfluoro-deca-B-methyl-para-carborane,” Angew. Chem. Int. Ed. 40, 2121 (2001).


475 Toralf Peymann, Carolyn Knobler, Saeed I. Khan and M. Frederick Hawthorne, “Dodeca(benzyloxy)dodecaborane,B12(OCH2Ph)12: A Stable Derivative of hypercloso-B12H12,” Angew. Chem. Int. Ed. 40, 1664 (2001). [pdf]


474 Andreas Maderna, Carolyn Knobler and M. Frederick Hawthorne, “Twelvefold Functionalization of an Icosahedral Surface by TotalEsterification of [B12(OH)12]2-: 12(12)-Closomers,” Angew. Chem. Int. Ed. 40, 1661 (2001). [pdf]


473 Toralf Peymann, Carolyn B. Knobler, Saeed I. Khan and M. Frederick Hawthorne, “Dodecamethyl-closo-dodecaborate(2-),” Inorg. Chem. 40, 1291 (2001). [pdf]
2000 472 Hans Lee, Carolyn B. Knobler and M. Frederick Hawthorne, “Supramolecular Self-Assembly Directed by Carborane C-H¼F Interactions,” Chem. Comm24, 2485 (2000).


471 Ibrahim H.A. Badr, R. Daniel Johnson, Martin Diaz, M. Frederick Hawthorne and Leonidas G.      Bachas, “A Selective Optical Sensor Based on [9]Mercuracarborand-3, A New Type of Ionopore with a Chloride Complexing Cavity,” Anal. Chem., 72, 4249 (2000).


470 Juston J. Rockwell, Axel Herzog, Toralf Peymann, Carolyn B. Knobler and M. Frederick  Hawthorne, “Recent Advances in the Field of Camouflaged Carboranes and Polyhedral Boranes,” Current Sci.78, 405 (2000).


469 Hans Lee, Martin Diaz, Carolyn Knobler and M. Frederick Hawthorne, “Octahedral Coordination of Iodide in an ElectrophilicSandwich,” Angew. Chem. Int. Ed.39, 776 (2000).


468 Toralf Peymann, Carolyn B. Knobler and M. Frederick Hawthorne, “A Study of the Sequential Acid-Catalyzed Hydroxylation ofDodecahydro-closo-Dodecaborate(2-),” Inorg. Chem., 39, 1163 (2000).


467 M. Frederick Hawthorne, “Broadening the Conflux of Boron and Carbon Chemistries,”  Proceedings of the Tenth International Conference on Boron Chemistry, Contemporary Boron Chemistry, Edited by M. Davidson, A.K. Hughes, T.B. Marder and K. Wade, Royal Society of Chemistry:  Cambridge, 197 (2000).


466 Weilin Chen, Martin Diaz, Juston Rockwell, Carolyn B. Knobler and M. Frederick Hawthorne,   “Synthesis and Characterization of Water-Soluble Boron-Substituted Ortho-Carborane Derivatives,” Comptes Rendus de l’Académie des Sciences – Série IIc –Chemie3, 223 (2000).

Back To Top